The Sample Submission model is the full-service SPR/BLI analysis option for investigators and is available for all platforms (SPR - Biacore 3000, Biacore S200, and Biacore T200; BLI - ForteBio OctetRED96)
Researchers will provide the samples of interest and all experimentation, optimization, and analysis will be performed by the Core Staff.
To submit samples for SPR analysis, all investigators are required to submit a Service Request on CoreResearch@Duke and make arrangements for sample drop-off. Information on how to complete a Service Request can be found in the BIA Core Facility User Guide. Sample preparation guidelines and the sample submission form can be found on the Sample Requirements & Submission page.
The Independent Use model is the self-service SPR analysis option for investigators.
Interested researchers will be trained in the independent operation of the Biacore T200 platform. Once trained and approved for use, researchers will be free to reserve and operate the instrument independently with 24/7/365 availability.
The BIA Core Facility Director, Manager, and Staff can be available to assist in the design and troubleshooting of experiments and/or analysis and interpretation of data. Please contact the Facility Manager (Brian Watts, Ph.D.) and/or the Facility Director (Munir Alam, Ph.D.) to schedule a consultation.
The BIA Core Facility endeavors to keep commonly used SPR sensor chips in stock for Sample Submission runs as well as Independent Users. All sensor chips are purchased directly from GE Biacore and offered at-cost to users of the facility. We generally maintain a stock of CM5 and Series S CM5 chips with limited availability of other chip types. Please contact the facility regarding purchase as availability cannot be guaranteed (see Rates for pricing).